Interferon-?, Interleukin 1-? and Tumor Necrosis Factor-? levels and Their Association with Lipid and Glycaemic Profiles in Diabetic Mice
نویسندگان
چکیده
The cytokines IFN-?, interleukin IL-1?, and TNF-? each up regulate the expression of major histocompatibility complex (MHC) are therefore considered as inflammatory markers. present study aimed to measure serum levels in mice after induction diabetes with streptozotocin correlate their lipid glycaemic profiles. included 40 Swiss Albino (20 males 20 females), half male female groups were made diabetic by intraperitoneal injection streptozotocin. After 48 hours, INF-?, IL1-? well measured ELISA correlated cytokines, profile, blood glucose insulin. three studied IL 1-? statistically significantly higher among compared control group. Diabetic (M-STZ mice) group showed profile (M-control). Cholesterol level was (F-control) M-control (F-STZ F-Control Regarding levels, there significant linear correlations glycemic (Glucose, insulin) reflected positive correlation negative insulin level.
منابع مشابه
the past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
چکیده ندارد.
Tumor Necrosis Factor-α and Interleukin-1- β Polymorphisms in Pre-Eclampsia
Background: Pre-eclampsia is the most common critical condition during pregnancy. Plasma concentrations of tumor necrosis factor-alpha (TNF-α) and interleukin-1-beta (IL-1β) increase in pregnant women with pre-eclampsia, compared to normal pregnant women. Objective: To investigate the polymorphisms of IL-1β (C+3954T), TNF-α (G- 308A), and (G-238A) in preeclemptic women northeastern Iran. Me...
متن کاملevolutionary origin and phylogenetic relationships among fusarium oxysporum f. sp. melonis isolates in iran and their relationship with nonpathogenic isolates
پژمردگی فوزاریومی خربزه و طالبی با عامل fusarium oxysporum f. sp. melonis از بیماری های مهم قارچی در مناطق رشد این گیاهان می باشد. جدایه های f. oxysporum از گیاهان و خاک ریزوسفر متعلق به پنج استان مهم تولیدکننده ی خربزه و طالبی جداسازی شد و بر پایه ی بیماری زایی در ارقام افتراقی، گروه های سازگاری رویشی (vegetative compatibility groups)، توالی سنجی ناحیه ی جداکننده ی بین ژنی دی اِن اِی ریبوزومی (n...
15 صفحه اولImpact of Metformin and Pioglitazone on Serum Level of Tumor Necrosis Factor-Alpha and Lipid Profiles during Implantation Window in Diabetic Rats
Objective Objectives: The present study was designed to evaluate the serum lipid profile and Tumor Necrosis Factor alpha (TNF-ɑ) level in diabetic rats at the time of implantation. Type 2 diabetes mellitus (T2DM) could affect various systems, including innate immune system and causes chronic low-grade inflammation which increases the level of TNF-ɑ. Furthermore, T2DM is often accompanied by imp...
متن کاملEvaluation of Brain Natriuretic Peptide, Tumor Necrosis Factor and Interleukin-6 Plasma Levels in Infants and Children with Congenital Heart Disease
Background Congenital heart disease (CHD) is the most common cause of major congenital birth defect. The aim of this study was to investigate the association of CHD with serum levels of Tumor necrosis factor-α (TNFα), Interleukin 6 (IL-6), and B-type Natriuretic Peptide (BNP) in infant and children. Materials and Methods The present study was conducted in Heshmat heart hospital and 17 Shahrivar...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Biochemistry Research and Review
سال: 2021
ISSN: ['2231-086X']
DOI: https://doi.org/10.9734/ijbcrr/2021/v30i130243